REGENERATIVE SKIN TREATMENT

Biostimulators

Injectable regenerative treatments — exosomes and polynucleotides — that stimulate the skin’s own repair and collagen rather than simply filling, to improve skin quality, hydration, elasticity and tone.

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THE PROMISE

Healthier skin from within. Naturally renewed.

What are Biostimulators

Biostimulators are injectable regenerative treatments that work by stimulating the skin’s own repair processes — encouraging it to produce fresh collagen, elastin and healthier tissue — rather than simply adding volume the way a traditional filler does. The aim is not to change your features, but to improve the quality of the skin itself: more hydrated, more elastic, more even and more refreshed.

At our clinic this approach centres on complementary regenerative treatments. Polynucleotides (PN) and PDRN are highly purified chains of nucleotides — the building blocks of DNA — that hydrate the skin and create an ideal environment for fibroblasts, the cells that produce collagen and elastin. They are related but not the same: we use both, and because PN have longer DNA chains than PDRN, they are the more premium and more costly of the two. Exosomes are tiny, cell-derived signalling vesicles that carry growth factors and other messengers which prompt skin cells to repair and renew.

Both are delivered into the skin by injection or, in some cases, with micro-needling, and are minimally invasive — a topical anaesthetic may be used for your comfort.

FROM INSTAGRAM

Real patient stories

Short videos Dr Karatzias has shared on Instagram.

Injection treatment at the temple, close-up

The neck and décolleté after treatment

The Procedure

After cleansing the skin, a topical anaesthetic may be applied for your comfort. Dr. Karatzias then delivers the treatment into the skin — by fine-needle injection or, where appropriate, with micro-needling — tailoring the choice of biostimulator and the areas treated to your skin and your goals. Because these treatments work with your body’s own renewal, results build gradually over the following weeks, and a short course of sessions is often recommended for the most refined result. The exact products and the right plan for you are always discussed and agreed at your consultation.

What it can help with

Injectable biostimulators may help to:

How the Patient Recovers

Biostimulators are minimally invasive, so most people return to their day soon afterwards. It is normal to have some redness, mild swelling or small injection marks at the treated sites, which usually settle within a short time. We give you a simple aftercare routine, and as with any skin treatment it is sensible to protect the area from direct sun and to use a broad-spectrum sun block while the skin settles.

Are You the Right Candidate?

Biostimulators suit people who would like to improve the quality and health of their skin — hydration, elasticity, tone and texture — in a natural, gradual way rather than with surgery or volume-based fillers. Suitability depends on your skin and your goals, and on your medical history; at your consultation Dr. Karatzias will assess your skin, explain which treatment is most appropriate for you, and recommend the right approach — including whether another treatment may suit you better.

To see if you are a candidate for this treatment or if you wish to learn more details about it, please complete our online consultation form or call us at +357 22 275522.

Results gallery

BEFORE & AFTER CASES

Results vary from person to person.

Frequently Asked Questions

Does the treatment hurt?

Most people find it very manageable. The treatment is delivered with a fine needle or micro-needling, and a topical anaesthetic may be applied beforehand for your comfort. Any sensation is usually brief and mild.

Is there any downtime?

Very little. Biostimulators are minimally invasive, so most people return to their day soon afterwards. Some redness, mild swelling or small injection marks at the treated sites are normal and usually settle within a short time; protecting the area from direct sun and using a broad-spectrum sun block while the skin settles is sensible.

When will I see results, and how long do they last?

Because these treatments work with your skin’s own renewal rather than simply filling, the change is gradual — results typically build over the following weeks rather than appearing instantly. How long the benefit lasts varies from person to person; refreshing your results periodically helps maintain skin quality over time.

How many sessions will I need?

A short course of sessions is often recommended for the most refined result, since the skin renews itself progressively. The exact number depends on your skin and your goals, and the right plan for you is discussed and agreed at your consultation.

Will my face still look natural?

Yes — that is the aim. Biostimulators improve the quality of the skin itself, rather than adding volume or changing your features, so the result reads as healthier, fresher, more even skin rather than a "done" or overfilled look.

How much does it cost?

Cost varies with the individual plan — which biostimulator is used, how many areas are treated and how many sessions are advised. The exact plan and pricing are discussed at your consultation, where Dr. Karatzias tailors the approach to your skin and goals. To learn more, complete our online consultation form or call us at +357 22 275522.

RELATED PROCEDURES

Often considered together.

PRP Facial

Using your own platelet-rich plasma to stimulate collagen and refresh skin quality — a natural partner to biostimulators.

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Dermal Fillers

Hyaluronic-acid fillers to restore volume and smooth lines, alongside skin-quality treatments.

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HIFU Lifting

Non-surgical ultrasound skin tightening that lifts from within, complementing regenerative skin care.

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Ready to start?

Book a consultation with Dr. Karatzias to discuss whether biostimulators are right for your skin. In-person in Cyprus.

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CALL +357 22 275522

Internationally Recognized

Staying at the forefront of medical advancement. Dr. Karatzias is proudly accredited by leading global organizations in both Plastic Surgery and Wound Management.

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